Alpha-terpineol: evaluation and pharmacological screening as an antidepressant agent

Objective: To evaluate the possible antidepressant effects of alpha-terpineol in rodents. Material and Methods: Depression levels were analyzed by comparing total immobility time presented animals experimental groups test session, using Forced Swimming Test Tail Suspension Test. The parameters locomotion (central, peripheral total) motor coordination evaluated Open Field Rota Rod Test, respectively. In second stage, involvement noradrenergic system action was investigated. Results Discussion: After performing tests, it observed that received had reduced compared to other groups. Rota-rod, mice showed, respectively, good exploratory activity during tests. addition, study Noradrenergic System proved be a promising mechanism used its action. Conclusion: view results similar responses those found monoterpenes investigated literature. Thus, is shown as clinically humans, with less side low production cost.